Compounded Semaglutide (GLP-1)
Starting From
$379.00
Key Benefits
A Compounded Semaglutide (GLP-1) injection designed to help manage appetite and support sustainable weight care while addressing underlying metabolic health factors for long-term results.
How it Works
Compounded Semaglutide (GLP-1) is a once-weekly injectable medication that mimics a natural hormone involved in appetite regulation and blood sugar control. It may support patients interested in weight management as part of a structured care plan.
Why It's Unique
Istryve provides access to compounded medications with licensed clinician oversight, making advanced therapies more affordable and approachable through a telehealth platform.
The Istryve Difference
Istryve weight loss program provides access to compounded medications therapies with licensed clinician oversight. Care is paired with transparent pricing, telehealth convenience, and ongoing support—helping you explore safe, science-driven options for reaching your health goals in a way that fits your lifestyle.
Istryve does not manufacture compounded medications. Actual product appearance and labeling of the medication you receive will differ from website images.
Compare Fridays vs the rest
Why pay more for less results?
Fridays GLP-1 doesn’t just cost less, it delivers more. More support, more flexibility, and more real results for your money. See how it stacks up:
Disclaimer: The information in this comparison chart is based on the best available data as of September 1, 2025. Some details may have changed since that time. For questions, please contact us at support@joinistryve.com. Fridays is not affiliated with, sponsored by, or endorsed by the other brands whose logos appear in this chart.
Get the answers you need
Find answers to frequently asked questions about our weight loss program and community.
Still have questions?
Who qualifies for weight loss medications?
While prescriptions for weight loss medication cannot be guaranteed for every patient, if you are 18 years of age or older and meet specific criteria such as weight and certain associated health conditions, your healthcare provider may consider you eligible for a prescription. Generally speaking, those who qualify are: individuals with overweight (BMI > 25) and those who are seeking maintenance therapy that have a BMI > 22 and if their current BMI < 27, have a history of obesity or overweight and have previously been on a GLP-1 within the past 12 months.
How old do I have to be to participate in the istryve program?
At this time, patients have to be at least 18 years old to participate in the program.
What is the cost of the weight loss program?
Fridays offers multiple subscription types, all of which include comprehensive coaching and services with no hidden fees, membership costs, or lab charges. Each plan provides regular virtual consultations with a clinician, prescription management and renewals (if applicable), support with insurance coverage for medications, and access to 1:1 nutritionist coaching, ongoing chat support, and health guides.
Subscription charges may appear on your credit card as “OPNLP FRIDAYS.”
Brand name medication pricing is based on insurance coverage.
Your clinical care team will work with you to identify the most affordable and suitable medication based on your health requirements and insurance coverage. GLP-1 prescriptions are usually more cost-effective when covered by insurance, but the exact expense will depend on your insurance plan. If you are uninsured, underinsured, or if the medication is not covered by your insurance, your provider may assist you in finding a prescription discount card or an alternative medication that is more cost effective.
What happens if my BMI falls below 25?
If your BMI drops below 25, it is possible that you may no longer require GLP-1 medications, and your insurance may no longer cover the cost of the medication. In this situation, your healthcare provider will reassess your eligibility to determine if you can continue with the program. There are patients that may require maintenance therapy even if their BMI drops below 25 and your healthcare provider will determine if this option is right for you.
Do you accept insurance?
At present, insurance coverage does not include virtual visits for our program.
What type of provider will I see during my visits?
Our team consists of physicians and licensed nurse practitioners who possess the qualifications to prescribe medications, order lab tests, and evaluate your symptoms and health objectives. They are well-equipped to develop a personalized care plan tailored to your specific needs.
Do you offer maintenance therapy?
Certainly! We offer maintenance therapy for patients in most cases, however, the only patients that don’t qualify for maintenance therapy are patients with a BMI < 22 and this is mainly because we’re a virtual platform and for this patient population it’s safer to provide maintenance therapy if they’re managed at a physical clinic. In order to qualify for maintenance therapy, a patient needs to have a previous diagnosis of obesity (BMI > 30) or overweight (BMI > 27) and have been on a GLP-1 medication within the past 12 months. You may take our quiz to see if you qualify for maintenance therapy!
Who should avoid taking a GLP-1 medication for weight loss?
If you meet any of the following criteria, you may not be eligible for a prescription of GLP-1 weight loss medication:
1. Currently pregnant, breastfeeding, or actively trying to become pregnant
2. End-stage kidney disease (on or about to be on dialysis)
3. End-stage liver disease (cirrhosis)
4. Active eating disorder or history of eating disorder (bulimia, anorexia, etc.)
5. Current suicidal thoughts and/or prior suicidal attempt
6. Cancer (active diagnosis or treatment)
7. Current or history of pancreatitis
8. History of organ transplant on anti-rejection medication
9. Severe gastrointestinal condition (gastroparesis, inflammatory bowel disease)
10. Personal or family history of medullary thyroid cancer or multiple endocrine neoplasia (MEN) type 2
Please note that these eligibility criteria are not exhaustive, and it is crucial to consult with your healthcare provider for a comprehensive assessment of your individual circumstances.
What comes with my Subscription?
With your monthly subscription, you gain access to a comprehensive suite of services designed to support your health and wellness journey. Here’s what you can expect:
Monthly Visits with a Licensed Clinician: As part of your membership, you’ll have access to regular monthly visits with a licensed clinician. These professionals are dedicated to providing personalized support and guidance tailored to your unique health needs.
Help with Prior Authorizations for GLP-1 Medications: Dealing with insurance can be complex, especially when it comes to prior authorizations for specific medications like GLP-1’s. We’re here to assist you through this process, ensuring you have access to the medications you need for managing your health effectively.
Weekly Group Coaching Sessions: Our weekly group coaching sessions cover essential aspects of health and wellness, including nutrition, mindset, and movement coaching. These sessions provide valuable support and education, empowering you to make sustainable lifestyle changes and achieve your health goals.
Comprehensive Lab Testing
Lab tests through Quest Diagnostics are fully included in your monthly subscription, with no additional fees.
Personalized Nutritionist Support
Enjoy 1:1 nutritionist support and ongoing chat access as part of your subscription, providing you with personalized guidance and advice.
Care Coaching
A dedicated Certified Medical Assistant to meet every other week and help with goal setting, planning and accountability coaching.
Whether you’re looking for personalized guidance, assistance with medication access, or support in adopting healthier habits, our monthly membership offers a comprehensive solution to help you thrive on your wellness journey.
Do I need to have lab work done before starting the program?
No, on your initial visit with your licensed provider, in addition to reviewing your health history and goals, your clinician will order any necessary lab work. This step ensures your suitability for our program and to determine which medications would be most optimal for your weight management.
The required labs typically encompass a comprehensive metabolic panel (CMP), hemoglobin A1C (HgbA1C), thyroid-stimulating hormone (TSH), and a lipid panel. If you’ve had these labs completed within the past 24 months, you may not need labs ordered during your initial consultation, but this decision will be made by your provider.
You may upload your previous lab results into your portal or submit it to: support@joinfridays.com where someone from our team will upload it to your chart for your provider to review before your initial visit. It’s important to note that periodic lab tests may be required to monitor your body’s response to the medication and ensure safety.
Do you help with prior authorizations?
Absolutely, we’re here to assist you every step of the way, including navigating the process of prior authorizations for medications, which includes GLP-1’s. Our team understands the complexities of insurance procedures, and we’re committed to ensuring that you have access to the medications prescribed by your healthcare provider. Your health and well-being are our top priorities, and we’re dedicated to making the process as smooth and stress-free as possible for you.
Where can I get my lab tests done?
You may visit the nearest Quest laboratory for your lab testing. If you have already completed the necessary lab tests within the past twelve months you may upload your previous lab results into your portal or submit it to: support@istryve.com where someone from our team will upload it to your chart for your provider to review before your initial visit. If you don’t live near a Quest lab, our providers can order a general lab requisition form but we recommend completing this at your PCP’s office as it can otherwise be pricey!
Will my information be confidential and private?
Yes. Rest assured that our services strictly adhere to HIPAA-compliance standards and privacy guidelines. We employ state-of-the-art technology to maintain the utmost security and confidentiality of your personal information. Your privacy is our priority, and we take every measure to ensure the protection of your sensitive data.
What is the cost of lab testing?
If you visit a Quest Diagnostics location, the cost of lab tests is fully covered as part of your monthly subscription, with no additional fees. However, you may decide to get your labs completed elsewhere. The cost of labs may also vary if you are using insurance or paying out-of-pocket. To determine whether lab testing is covered by your insurance plan, we recommend reaching out to your insurance carrier directly.
What is your refund and cancellation policy?
Our program is a month-to-month commitment. We provide options for refunds or early cancellation:
1. If you are deemed ineligible for the program based on new lab results or unforeseen factors that emerge after at least one virtual consult, you may cancel immediately. However, please note that refunds for prior months will not be issued.
2. If the medication’s cost makes it financially impractical for you to continue with the program, you may cancel immediately. However, please be aware that refunds for prior months will not be granted.
3. You may cancel at any time and will receive a full refund for the current billing cycle as long as you haven’t had your visit for the month. Refunds for prior months will not be issued.
If you have any inquiries or wish to request a refund or cancellation, please reach out to our dedicated customer care team at support@istryve.com. We will be more than happy to assist you.